发明名称 |
Polypeptides from the Group B Streptococcus (GBS) and uses thereof in treating and detecting GBS disease or infection |
摘要 |
Disclosed is a polypeptide from the Group B streptococcus (GBS) comprising of at least 70 amino acids of SEQ ID NO:20906. Further described are fusion proteins comprising the said protein and at least 7 amino acids from the polypeptide sequences (even numbers) from the group of SEQ ID NO: 2-22740. The said proteins are used for the treatment of GBS infection and/or disease, generating antibodies and also in vaccines. Also disclosed is the use of the nucleotide sequences encoding for the above polypeptides and use as therapeutics (odd numbers 1-22740).
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申请公布号 |
NZ555934(A) |
申请公布日期 |
2010.04.30 |
申请号 |
NZ20050555934 |
申请日期 |
2005.12.21 |
申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS, INC.;J. CRAIG VENTER INSTITUTE, INC. |
发明人 |
TETTELIN, HERVE;MASIGNANI, VEGA |
分类号 |
C07K14/315;C07K16/12;C12N15/31 |
主分类号 |
C07K14/315 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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