发明名称 |
PYRROLOTRIAZINE COMPOUNDS AS KINASE INHIBITORS |
摘要 |
<p>The present invention provides compounds of formula I
and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.</p> |
申请公布号 |
SI1699797(T1) |
申请公布日期 |
2010.04.30 |
申请号 |
SI20040031286T |
申请日期 |
2004.12.23 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
FINK BRIAN E.;GAVAI ASHVINIKUMAR V.;VITE GREGORY D.;CHEN PING;MASTALERZ HAROLD;NORRIS DEREK J.;TOKARSKI JOHN S.;ZHAO YUFEN;HAN WEN-CHING |
分类号 |
A61K31/53;C07D487/04;C07D519/00 |
主分类号 |
A61K31/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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