6-phenyl-1H-imidazo[4, 5-C]pyridine-4-carbonitrile derivatives as cathepsin K and S inhibitors

摘要

Disclosed is 6-phenyl-1H-imidazo[4,5-C]pyridine-4-carbonitrile derivatives having the general Formula I, wherein the substituents are listed in the specification and pharmaceutical compositions comprising the same as well as the use of these derivatives for the preparation of medicament for the treatment of cathepsin K and/or cathepsin S related diseases such as osteoporosis, atherosclerosis and immune disorders.