发明名称 |
PHARMACEUTICAL COMPOSITION FOR TREATING ALCOHOL-INDUCED LIVER INJURY COMPRISING (4S,5S)-5-FLUOROMETHYL-5-HYDROXY-4-((((5R)-5-ISOPROPYL-3-(ISOQUINOLIN-1-YL)-4,5-DIHYDRO-5-ISOXAZOLYL)CARBONYL)AMINO)-DIHYDROFURAN-2-ONE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF |
摘要 |
PURPOSE: A pharmaceutical composition for a liver damage treatment caused by alcohol is provided to effectively control apoptosis by reducing caspase at the liver damage caused by the alcohol. CONSTITUTION: A pharmaceutical composition for a liver damage treatment caused by alcohol contains CF1 marked as the chemical formula 1, or its pharmaceutically allowable salt. The liver damage caused by the alcohol includes fatty liver, alcoholic hepatitis, and alcoholic cirrhosis. CF1 is synthesized from the mixture of compounds marked as the chemical formula 6 and the chemical formula 7. The pharmaceutical composition is in a form of a tablet or a capsule.
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申请公布号 |
KR20100044647(A) |
申请公布日期 |
2010.04.30 |
申请号 |
KR20080103859 |
申请日期 |
2008.10.22 |
申请人 |
LG LIFE SCIENCES LTD. |
发明人 |
CHANG, HYE KYUNG;OH, YEONG SOO;SHIN, HYUN IK;PARK, MI JEONG;PARK, JUNG GYU;PAIK, YONG HAN |
分类号 |
A61K31/4725;A61K31/42;A61P1/16 |
主分类号 |
A61K31/4725 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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