发明名称 New disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
摘要 Disclosed is a compound of Formula 1 wherein R1 is selected from the group consisting of -CN, -OCF3, -OCHF2, -SCF3, -SCHF2, -CF3, F, Cl, -CH3 and -OCH3; R2 is selected from the group consisting of F, Cl, Br, and CH3; R3 is selected from the group consisting of C1-C3- alkyls and allyl, provided that when R1 is CN or CF3, R3 can only be C1-C2 alkyls; or a pharmaceutically acceptable salt thereof. Disclosed are intermediates and the use of a compound of Formula 1 in the manufacture of a pharmaceutically active preparation for treating a disorder of the central nervous system.
申请公布号 NZ552409(A) 申请公布日期 2010.04.30
申请号 NZ20050552409 申请日期 2005.06.08
申请人 NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE 发明人 SONESSON, CLAS;SWANSON, LARS;WATERS, NICHOLAS
分类号 A61K31/451;A61K31/495;A61P25/00;C07D211/18;C07D211/22;C07D211/52;C07D295/06;C07D295/14 主分类号 A61K31/451
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