| 摘要 |
PROBLEM TO BE SOLVED: To provide compounds for inactivating pathogens in materials. SOLUTION: Compounds and methods for inactivating pathogens in materials are described, including compositions and methods for inactivating pathogens in red blood cell preparations and biological materials such as plasma. The compounds and methods may be used to treat materials for in vitro or in vivo use, such as clinical testing or transfusion. The compounds are designed to specifically bind to and react with nucleic acid, and then to degrade to form degraded products. The degradation reaction is preferably slower than reactions with nucleic acid. COPYRIGHT: (C)2010,JPO&INPIT
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