ANTI-CD8 ANTIBODIES BLOCK PRIMING OF CYTOTOXIC EFFECTORS AND LEAD TO GENERATION OF REGULATORY CD8+T CELLS
摘要
The present invention includes compositions and methods for inducing tolerance in a subject in need thereof comprising providing the subject with an effective amount of an anti-CD8 antibody sufficient in induce CD8+ T cell immune tolerance to allogeneic antigens.
申请公布号
WO2009149382(A3)
申请公布日期
2010.04.29
申请号
WO2009US46464
申请日期
2009.06.05
申请人
BAYLOR RESEARCH INSTITUTE;BANCHEREAU, JACQUES, F.;KLECHEVSKY, EYNAV;PALUCKA, ANNA, KAROLINA