发明名称 STABLE DIGESTIVE ENZYME COMPOSITIONS, METHODS OF PRODUCING THE SAME AND USES THEREOF
摘要 Compositions of the present invention, comprising at least one digestive enzyme (e.g., pancrelipase) are useful for treating or preventing disorders associated with digestive enzyme deficiencies. The compositions of the present invention can comprise a plurality of coated particles, each of which is comprised of a core coated with an enteric coating comprising at least one enteric polymer and 4-10% of at least one alkalinizing agent, or have moisture contents of about 3% or less, water activities of about 0.6 or less, or exhibit a loss of activity of no more than about 15% after six months of accelerated stability testing.
申请公布号 IL200407(D0) 申请公布日期 2010.04.29
申请号 IL20090200407 申请日期 2009.08.13
申请人 EURAND PHARMACEUTICALS LIMITED 发明人
分类号 A61K 主分类号 A61K
代理机构 代理人
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