发明名称 |
AZOLOPYRROLONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS |
摘要 |
<p>The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula (I) including all pharmaceutically acceptable salts and stereoisomers thereof: wherein A is a monocyclic aryl or monocyclic heteroaryl; W is a direct bond, -0-, or -N(R6)-, provided that if W is a direct bond, D must be a cyclic amine that is attached to A via the nitrogen atom of said cyclic amine; D is a direct bond, substituted or unsubstituted C1 to C4 alkyl, substituted or unsubstituted C3 to C7 cycloalkyl, cycloalkylalkyl, or a 4 to 6 membered cyclic amine; B and E are independently N or CH provided that both are not CH;</p> |
申请公布号 |
WO2010047956(A1) |
申请公布日期 |
2010.04.29 |
申请号 |
WO2009US59924 |
申请日期 |
2009.10.08 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY;DEVASTHALE, PRATIK;WASHBURN, WILLIAM, N.;WANG, WEI;HERNANDEZ, ANDRES;AHMAD, SALEEM;ZHAO, GUOHUA |
发明人 |
DEVASTHALE, PRATIK;WASHBURN, WILLIAM, N.;WANG, WEI;HERNANDEZ, ANDRES;AHMAD, SALEEM;ZHAO, GUOHUA |
分类号 |
C07D487/04;A61K31/4015;A61P3/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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