| 摘要 |
<p>A process for the preparation of nanoparticles comprising an active hydrophobic compound, the process comprising the steps of: a) providing a first stream comprising the compound, a hydrophobic polymer, an amphiphilic polymer and a solvent; b) providing a second stream comprising an antisolvent; c) rapidly intermixing the first and second streams in a precipitation chamber thereby forming the nanoparticles; and d) rapidly intermixing the intermixed first and second streams with a third steam comprising a stabilising agent.</p> |
