发明名称 PROCESS FOR THE PREPARATION OF DIHYDROXY ESTERS AND DERIVATIVES THEREOF
摘要 A process is provided for the preparation of a compound of formula (5) wherein R represents an optionally substituted hydrocarbyl group and X represents a hydrocarbyl linking group. The process comprises either the stereoselective reduction of the keto group in a dihydroxy keto precursor followed by selective esterification of a primary hydroxy, or selective esterification of a primary hydroxy of a dihydroxy keto precursor followed by stereoselective reduction of the keto group.
申请公布号 IL193404(A) 申请公布日期 2010.04.29
申请号 IL20080193404 申请日期 2008.08.12
申请人 ASTRAZENECA UK LIMITED 发明人
分类号 C07C67/03;C07C69/675;C07D319/06;C12N9/20;C12P7/62;C12P17/06;C12R1/84 主分类号 C07C67/03
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