发明名称 3-AMINO-PYRROLO [3,4-C]PYRAZOLE-5 (1H,4H,6H)CARBALDEHYDE DERIVATIVES AS PKC INHIBITORS
摘要 The present invention relates to compounds and pharmaceutically acceptable salts of Formulas A and B: (A) and (B) wherein A, B, R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications, cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, Alzheimer's disease and dermatological disease pression, virus diseases, inflammatory disorders, or diseases in which the liver is a target organ.
申请公布号 IL200270(D0) 申请公布日期 2010.04.29
申请号 IL20090200270 申请日期 2009.08.06
申请人 PFIZER INC. 发明人
分类号 C07D 主分类号 C07D
代理机构 代理人
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