发明名称 |
PEPTIDE AND USES THEREOF |
摘要 |
A method of inhibiting activity of a cathepsin L-like protease in cells or tissue and the use of the method in the treatment of disease such as cancer and inflammatory diseases is described. The method comprises administration of a cathepsin propeptide or a nucleic acid encoding a cathepsin propeptide. In particular embodiments, the propeptide is a Cathepsin S propeptide. Further, the use of propeptides having an Fc portion is described.
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申请公布号 |
US2010104554(A1) |
申请公布日期 |
2010.04.29 |
申请号 |
US20070281356 |
申请日期 |
2007.03.02 |
申请人 |
FUSION ANTIBODIES LIMITED, A CORPORATION OF GREATBRITIAN |
发明人 |
SCOTT CHRISTOPHER;BURDEN ROBERTA;JOHNSTON JIM;MCCURLEY MARK;SNODDY PHILIP;BUICK RICHARD |
分类号 |
A61K39/395;A61K31/7088;A61K38/00;A61K38/48;C12N9/64;C12P21/06 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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