发明名称 |
Enhancing Efficacy of Vaccines Administered Via the Respiratory Tract |
摘要 |
Disclosed herein are vaccine compositions comprising live attenuated virus with anti-antibody to improve efficacy. Specifically exemplified herein is a composition comprising live attenuated cold adapted influenza virus and an enhancing amount of IgG anti-IgA antibody to temporarily inactivate IgA defenses. Also disclosed herein are methods of immunizing a subject to protect against influenza comprising administering compositions taught herein.
|
申请公布号 |
US2010104562(A1) |
申请公布日期 |
2010.04.29 |
申请号 |
US20080525735 |
申请日期 |
2008.03.19 |
申请人 |
SMALL JR PARKER A;BENDER BRADLEY S |
发明人 |
SMALL, JR. PARKER A.;BENDER BRADLEY S. |
分类号 |
A61K39/395;A61P37/00 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|