发明名称 NAPHTHALENE AND QUINOLINE SULFONYLUREA DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS
摘要 The invention is directed to naphthalene and quinoline sulfonylurea derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included.
申请公布号 US2010105718(A1) 申请公布日期 2010.04.29
申请号 US20080529271 申请日期 2008.03.25
申请人 MERCK FROSST CANADA LTD. 发明人 BURCH JASON;FARAND JULIE;HAN YONGXIN;STURINO CLAUDIO
分类号 A61K31/437;A61K31/403;C07D209/56;C07D471/04 主分类号 A61K31/437
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