The present invention relates to prodrugs of vascular disrupting agents comprising a vascular disrupting agent (VDA) associated with a MMP proteolytic cleavage site and to the use of such prodrugs in the targeted treatment of cancer.
申请公布号
WO2010046628(A1)
申请公布日期
2010.04.29
申请号
WO2009GB02484
申请日期
2009.10.20
申请人
UNIVERSITY OF BRADFORD;FALCONER, ROBERT, ANDREW;GILL, JASON;ATKINSON, JENNIFER;LOADMAN, PAUL;BIBBY, MICHAEL;PATTERSON, LAURENCE
