| 发明名称 |
METHODS OF USING MEVALONATE DECARBOXYLASE (MVD) ANTAGONISTS |
| 摘要 |
<p>The present invention provides novel methods of reducing Flavivirus viral replication and/or infection, e.g., Dengue virus. The invention employs mevalonate decarboxylase (MVD) antagonists to inhibit the cholesterol biosynthesis pathway, thereby inhibiting viral replication / infection.</p> |
| 申请公布号 |
WO2010046401(A1) |
申请公布日期 |
2010.04.29 |
| 申请号 |
WO2009EP63816 |
申请日期 |
2009.10.21 |
| 申请人 |
NOVARTIS AG;BORAWSKI, JASON;GAITHER, LARRY ALEXANDER;LABOW, MARK ARON |
发明人 |
BORAWSKI, JASON;GAITHER, LARRY ALEXANDER;LABOW, MARK ARON |
| 分类号 |
A61K31/366;A61K31/7088;A61P31/14;C12N9/88 |
主分类号 |
A61K31/366 |
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