发明名称 Lipidated imidazoquinoline derivatives
摘要 <p>The compounds of the subject invention are adjuvant molecules that comprise an imidazoquinoline molecule covalently linked to a phospho- or phosphonolipid group. The compounds of the invention have been shown to be inducers of interferon-a, IL-12 and other immunostimulatory cytokines and possess an improved activity profile in comparison to known cytokine inducers when used as adjuvants for vaccine antigens.</p>
申请公布号 AU2009308278(A1) 申请公布日期 2010.04.29
申请号 AU20090308278 申请日期 2009.10.23
申请人 GLAXOSMITHKLINE BIOLOGICALS SA 发明人 DAVID JOHNSON
分类号 C07K16/46;A61K39/395 主分类号 C07K16/46
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