Use of mesenchymal stem cells for treating osteoporosis
摘要
The osteoporosis treatment and infusion compositions of the invention increase the number of the patient's own progenitor cells (hMSCs) and the reservoir of available bone-forming osteoblasts. They can be used to generate cortical and cancellous bone which has been lost as a result of post-menopausal osteoporosis, male idiopathic osteoporosis, congenital osteoporosis and other bone resorption diseases. Most cases of osteoporosis can be treated with a metered intravenous infusion of the composition of the invention over the course of 15-30 minutes, using customary cell reinfusion therapy techniques.
申请公布号
EP2179738(A2)
申请公布日期
2010.04.28
申请号
EP20100000798
申请日期
1998.01.22
申请人
OSIRIS THERAPEUTICS, INC.;CASE WESTERN RESERVE UNIVERSITY
发明人
BRUDER, SCOTT, P.;CAPLAN, ARNOLD, I.;BURNS, JAMES, S.;MARSHAK, DANIEL