发明名称 |
3-substituted-[1,2,3]benzotriazinone compounds for enhancing glutamatergic synaptic responses |
摘要 |
This invention relates to the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. These brain networks are involved in cognitive abilities related to memory impairment, such as is observed in a variety of dementias and in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia and affective disorders. In a particular aspect, the present invention relates to compounds useful for treatment of such conditions, and methods of using these compounds for such treatment. |
申请公布号 |
ZA200905065(B) |
申请公布日期 |
2010.04.28 |
申请号 |
ZA20090005065 |
申请日期 |
2009.07.20 |
申请人 |
CORTEX PHARMACEUTICALS INC. |
发明人 |
MUELLER, RUDOLF;LEE, STEPHEN;O'HARE, SEAN;ROGERS, GARY;RACHWAL, STAN;STREET, LESLIE |
分类号 |
A01N;A61K |
主分类号 |
A01N |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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