发明名称 |
Immunogens for meningitidis-a vaccines |
摘要 |
An oligosaccharide useful for a Meningitidis A vaccine contains a first mannose unit having a spacer in the alpha configuration at C-1, which spacer is capable of conjugating to a protein, and which is connected to a second mannose unit through a 1,6-linkage which connects C-6 of the first unit to C-1 of the second unit, wherein the 1,6-linkage comprises a phosphonate. Related methods of making such compounds, analogous compounds, or intermediates thereof are also disclosed. |
申请公布号 |
ZA200710558(B) |
申请公布日期 |
2010.04.28 |
申请号 |
ZA20070010558 |
申请日期 |
2007.12.04 |
申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS S.R.L.;OSCARSON, STEFAN;TEODOROVIC, PETER |
发明人 |
OSCARSON, STEFAN;COSTANTINO, PAOLO;TEODOROVIC, PETER |
分类号 |
A61K;A61P;C07H |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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