发明名称 |
METHOD FOR PURIFYING OR DETECTING A TARGET PROTEIN |
摘要 |
Purifying or detecting a target protein (I) in a solution that may also contain a homolog of (I) comprises first contacting the solution with an aptamer that specifically binds to (I) but not to its homolog. An independent claim is also included for selecting an aptamer as above by contacting a mixture of aptamers with the homolog, recovering aptamers that do not bind to the homolog, contacting these aptamers with (I), separating unbound aptamers from aptamer-target complexes, dissociating the complexes, amplifying the dissociated aptamers and repeating the above steps. |
申请公布号 |
EP2178901(A2) |
申请公布日期 |
2010.04.28 |
申请号 |
EP20080827918 |
申请日期 |
2008.08.13 |
申请人 |
LFB BIOTECHNOLOGIES |
发明人 |
SIRET, LAURENT;CHTOUROU, ABDESSATAR;DHAINAUT, FREDERIC;PERRET, GERALD |
分类号 |
C07K1/22;C12N15/115;G01N33/68 |
主分类号 |
C07K1/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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