发明名称 |
Process for producing nitrogenous 5-membered cyclic compound |
摘要 |
A method of the intramolecular and intermolecular cyclization of an N-acylhydrazone for obtaining a pyrazoline skeleton or pyrazolidine skeleton under ordinary conditions with high stereoselectivity and in high yield. An N-acylhydrazone represented by the following formula (I): (wherein R1 and R2 are the same or different and each represents hydrogen or a hydrocarbon group and Ar represents an optionally substituted aromatic hydrocarbon group) is converted to an N-acylpyrazoline derivative with high stereoselectivity in the presence of a Lewis acid catalyst or asymmetric Lewis acid catalyst.
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申请公布号 |
US7705161(B2) |
申请公布日期 |
2010.04.27 |
申请号 |
US20050592139 |
申请日期 |
2005.02.21 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
KOBAYASHI SHU;YAMASHITA YASUHIRO |
分类号 |
C07D231/06;C07B53/00;C07B61/00;C07D231/04;C07D231/12;C07D231/18;C07D231/20;C07D401/06 |
主分类号 |
C07D231/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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