发明名称 Dendritic and star-shaped contrast agents for medical devices and bioabsorbable radiopaque bulk material and method for producing same
摘要 In accordance with the present invention, a high intensity radiopaque contrast agent is disclosed. The agent may be coated on or incorporated within bulk materials, which may then be subsequently utilized to fabricate a radiopaque medical device. Primary effects through chemistry include higher radiopaque concentrations per unit weight of the radiopaque element or agent. Secondary effects include selective placement of the radiopaque elements which may further enhance the radiopacity of the device with reduced requirements of the radiopaque agent. Such a radiopaque contrast agent may be produced in various forms such as a dendrimer and/or incorporated as the end groups of polymeric chain. In addition one can incorporate biological and/or pharmaceutical agents in combination with the present invention.
申请公布号 US7704488(B2) 申请公布日期 2010.04.27
申请号 US20080050996 申请日期 2008.03.19
申请人 CORDIS CORPORATION 发明人 ZHAO JONATHON Z.
分类号 A61K49/04 主分类号 A61K49/04
代理机构 代理人
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