发明名称 METHOD OF SYPHILIS TREATMENT
摘要 FIELD: medicine. ^ SUBSTANCE: syphilis treatment is ensured by specific therapy with benzylpenicillin combined with and nonspecific therapy with trental. Benzylpenicillin is introduced intravenously drop-by-drop in a dose 10000000 UN per 400 ml of physiological solution twice a day within two courses every 2 weeks. Trental is introduced with underlying specific therapy and between the courses in a dose 0.4 g 3 times a day. The total therapeutic course is 40-42 days. Introduction of trental allows improving the condition of vascular endothelium, including hematoencephalic barrier (HEB), ensuring removal of obstacles for penicillin penetration into HEB spinal fluid. ^ EFFECT: higher clinical effectiveness for nervous system disturbance, prevented ion of late vascular complications in syphilis. ^ 1 tbl, 3 ex
申请公布号 RU2387450(C1) 申请公布日期 2010.04.27
申请号 RU20080139349 申请日期 2008.10.02
申请人 FEDERAL'NOE GOSUDARSTVENNOE UCHREZHDENIE "URAL'SKIJ NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT DERMATOVENEROLOGII I IMMUNOPATOLOGII FEDERAL'NOGO AGENTSTVA POVYSOKOTEKHNOLOGICHNOJ MEDITSINSKOJ POMOSHCHI" (FGU "URNIIDVII ROSMEDTEKHNOLOGIJ") 发明人 KUNGUROV NIKOLAJ VASIL'EVICH;SURGANOVA VERA IVANOVNA;BAZARNYJ VLADIMIR VIKTOROVICH;KARBOVNICHAJA ELENA ALEKSANDROVNA
分类号 A61K31/43;A61K31/522;A61P25/16 主分类号 A61K31/43
代理机构 代理人
主权项
地址