发明名称 |
METHOD OF SYPHILIS TREATMENT |
摘要 |
FIELD: medicine. ^ SUBSTANCE: syphilis treatment is ensured by specific therapy with benzylpenicillin combined with and nonspecific therapy with trental. Benzylpenicillin is introduced intravenously drop-by-drop in a dose 10000000 UN per 400 ml of physiological solution twice a day within two courses every 2 weeks. Trental is introduced with underlying specific therapy and between the courses in a dose 0.4 g 3 times a day. The total therapeutic course is 40-42 days. Introduction of trental allows improving the condition of vascular endothelium, including hematoencephalic barrier (HEB), ensuring removal of obstacles for penicillin penetration into HEB spinal fluid. ^ EFFECT: higher clinical effectiveness for nervous system disturbance, prevented ion of late vascular complications in syphilis. ^ 1 tbl, 3 ex |
申请公布号 |
RU2387450(C1) |
申请公布日期 |
2010.04.27 |
申请号 |
RU20080139349 |
申请日期 |
2008.10.02 |
申请人 |
FEDERAL'NOE GOSUDARSTVENNOE UCHREZHDENIE "URAL'SKIJ NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT DERMATOVENEROLOGII I IMMUNOPATOLOGII FEDERAL'NOGO AGENTSTVA POVYSOKOTEKHNOLOGICHNOJ MEDITSINSKOJ POMOSHCHI" (FGU "URNIIDVII ROSMEDTEKHNOLOGIJ") |
发明人 |
KUNGUROV NIKOLAJ VASIL'EVICH;SURGANOVA VERA IVANOVNA;BAZARNYJ VLADIMIR VIKTOROVICH;KARBOVNICHAJA ELENA ALEKSANDROVNA |
分类号 |
A61K31/43;A61K31/522;A61P25/16 |
主分类号 |
A61K31/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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