发明名称 HYDROQUINONE DERIVATIVE HAVING ANTI-INFLAMMATORY AND IMMONO-SUPPRESSIVE EFFECTS AND THE PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
摘要 PURPOSE: A hydroquinone(HQ) derivative having anti-inflammation and immunity properties is provided to reduce NO generation by suppressing PDK1/Akt(protein kinase B) and to treat or prevent inflammation and septic shock. CONSTITUTION: A hydroquinone derivative compound is denoted by chemical formula 1. The hydroquinone derivative compound is 2-Allylbenzene-1,4-diol, (E)-2-(4-Hydroxy-3-methylbut-2-enyl)benzene-1,4-diol, (E)-2-(3-Methylnon-2-enyl)benzene-1,4-diol, (E)-2-(9-Hydroxy-3-methylnon-2-enyl) benzene-1,4-diol, and (E) -2 - (3-Methylhex-2-enyl) benzene-1,4-diol. A composition for preventing or treating septic shock contains the hydroquinone derivative compound of chemical formula 1. A health food for preventing or treating septic shock contains the hydroquinone derivative compound and a sitologically acceptable food supplement.
申请公布号 KR100954103(B1) 申请公布日期 2010.04.23
申请号 KR20090115946 申请日期 2009.11.27
申请人 KNU-INDUSTRY COOPERATION FOUNDATION 发明人 CHO, JAE YOUL;LEE, YONG GYU;KIM, SANG HEE
分类号 A61K31/05;A23L1/30;A61P29/00 主分类号 A61K31/05
代理机构 代理人
主权项
地址