| 摘要 |
The invention relates to tricyclic N-heteroaryl-carboxamide derivatives having formula (I) wherein: A represents, together with the Z-Zbond of the bicycle to which it is bound, a C-C-cycloalkyl group, a monocyclic heteroaryl or a monocyclic heterocycle with 4 to 7 members comprising between one and three heteroatoms selected from among O, S or N, including atoms Zand Z; Z, Z, Z, Zand Zrepresent, independently of each other, a nitrogen atom, a carbon atom or a C-Rgroup; Z, Z, Zand Zrepresent, independently of each other, a nitrogen atom or a carbon atom and Z, Z, Z, Z, Z, Z, Z, Zand Ztogether form a bicyclic heteroaryl linked to the nitrogen atom of the amide or thioamide having formula (I) by positions Z, Z, Zor Zwhen said positions correspond to a carbon atom, at least one of Z, Z, Z, Z, Zand Zcorresponding to a nitrogen atom; W represents an oxygen or sulphur atom; and P represents an indolyl, pyrrolo[2,3-c]pyridinyl, pyrrolo[2,3-6]pyridinyl, pyrrolo[3,2-/}]pyridinyl or pyrrolo[3,2-c]pyridinyl group, said group being substituted. The invention also relates to a method for preparing same and to the therapeutic use thereof.
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