| 发明名称 |
1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR TREATMENT OF COGNITIVE IMPAIRMENT |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a compound useful for the treatment of cognitive impairment, especially in a depressed patient. <P>SOLUTION: The compound is 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine, exhibits potent activity on SERT, 5-HT<SB>3</SB>, and 5-HT<SB>1A</SB>, and is useful for treatment of cognitive impairment, especially for the treatment of cognitive impairment in a depressed patient. <P>COPYRIGHT: (C)2010,JPO&INPIT |
| 申请公布号 |
JP2010090165(A) |
申请公布日期 |
2010.04.22 |
| 申请号 |
JP20090295187 |
申请日期 |
2009.12.25 |
| 申请人 |
H LUNDBECK AS |
发明人 |
BANG-ANDERSEN BENNY;FALDT ANDRE;MOERK ARNE;LOPEZ DE DIEGO HEIDI;HOLM RENE;STENSBOEL TINE BRYAN;RINGGAARD LONE MUNCH;MEALY MICHAEL J;ROCK MICHAEL HAROLD;BRODERSEN JOERGEN;JOERGENSEN MORTEN;MOORE NICHOLAS |
| 分类号 |
C07D295/08;A61K9/20;A61K31/495;A61K47/04;A61K47/12;A61K47/32;A61K47/36;A61K47/38;A61P1/08;A61P11/16;A61P13/10;A61P25/04;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P25/36;C07B61/00 |
主分类号 |
C07D295/08 |
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