| 发明名称 |
Co-crystals of tramadol and NSAIDs |
| 摘要 |
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
In a preferred embodiment, co-crystals of (-)tramadol-(S)-naproxen (1:2) and (+)tramadol-(R)-naproxen (1:2) are prepared. |
| 申请公布号 |
AU2009304235(A1) |
申请公布日期 |
2010.04.22 |
| 申请号 |
AU20090304235 |
申请日期 |
2009.10.16 |
| 申请人 |
LABORATORIOS DEL DR. ESTEVE, S.A. |
发明人 |
HELMUT HEINRICH BUSCHMANN;LLUIS SOLA CARANDELL;JORDI BENET BUCHHOLZ;JORDI CARLES CERON BERTRAN;CARLOS RAMON PLATA SALAMAN;NICOLAS TESSON |
| 分类号 |
C07C59/64;A61K31/135;A61K31/192;A61P25/04;A61P29/00;C07C217/74 |
主分类号 |
C07C59/64 |
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