发明名称 |
METHODS FOR JOINT LUBRICATION AND CARTILAGE WEAR PREVENTION MAKING USE OF GLYCEROPHOSPHOLIPIDS |
摘要 |
The present invention concerns methods of joint lubrication and/or prevention of cartilage wear making use of liposomes having membranes with at least one phospholipid (PL) of the group consisting of a glycerophospholipid (GPL) having two, being the same or different, C12-C16 hydrocarbon chain and a sphingolipid (SPL) having a C12-C15 hydrocarbon chain, the one or more membranes having a phase transition temperature in which solid ordered (SO) to liquid disordered (LD) phase transition occurs, the phase transition temperature being within a temperature of about 20° C. to about 39° C. for lubrication of joints.
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申请公布号 |
US2010098749(A1) |
申请公布日期 |
2010.04.22 |
申请号 |
US20090411855 |
申请日期 |
2009.03.26 |
申请人 |
HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED;TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.;YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITY OF JERUSALEM |
发明人 |
BARENHOLZ YECHEZKEL;NITZAN DORIT;ETSION IZHAK;SCHROEDER AVI;HALPERIN GRIGORY;SIVAN SARIT |
分类号 |
A61K9/127 |
主分类号 |
A61K9/127 |
代理机构 |
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地址 |
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