USE OF SERUM/PLASMA MICRORNA IN EARLY DIAGNOSIS OF HBV INFECTION AND LIVER CANCER

摘要

A microRNA combination used for distinguishing HCV-infected persons, HBV-infected persons and HBV-related liver cancer patients from normal persons as well as the use thereof in early diagnosis of HBV infection and HBV-related liver cancer are provided. The combination contains all the serum/plasma microRNAs which have different expression profiles between HCV-infected persons, HBV-infected persons, HBV-related liver cancer patients and normal persons. A kit containing the microRNAs of the combination used for early diagnosis of HBV infection and HBV-positive liver cancer as well as the preparation method thereof are further provided. The main advantages of the kit include high specificity and high sensitivity.