摘要 |
<p>The present invention discloses 3-hydroquinazolin-4-one derivatives for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cancer, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.</p> |
申请人 |
GILEAD PALO ALTO, INC.;GLUSHKOV, ANDREI;KOLTUN, DMITRY;MAYBORODA, ELENA;PARKHILL, ERIC;VASILVEVICH, NATALYA;ZABLOCKI, JEFF |
发明人 |
GLUSHKOV, ANDREI;KOLTUN, DMITRY;MAYBORODA, ELENA;PARKHILL, ERIC;VASILVEVICH, NATALYA;ZABLOCKI, JEFF |