| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for producing nanoparticles of a poorly water-soluble or substantially water-insoluble compound applicable for pharmaceuticals, foods, and cosmetics. <P>SOLUTION: The nanometer-size particles of a poorly water-soluble or substantially water-insoluble compound are produced by finely spraying a solution of the compound as a non-aqueous solvent or a mixture of an aqueous solvent and a non-aqueous solvent into a heated and fluidized bed of carrier excipient. The resulting product consists of a free flowing mixture of relatively large particles of the carrier excipient and the nanometer-size particles (not greater than 3 μm) of the compound. <P>COPYRIGHT: (C)2010,JPO&INPIT |
