| 发明名称 |
NOVEL CRYSTALS AND PROCESS OF MAKING 5-({[2-AMINO-3-(4-CARBAMOYL-2,6-DIMETHYL-PHENYL)-PROPIONYL]-[1-(4-PHENYL-1H-IMIDAZOL-2-YL)-ETHYL]-AMINO}-METHYL)-2-METHOXY- BENZOIC ACID |
| 摘要 |
<p>The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid.</p> |
| 申请公布号 |
EP2176234(A2) |
申请公布日期 |
2010.04.21 |
| 申请号 |
EP20080781434 |
申请日期 |
2008.07.07 |
| 申请人 |
JANSSEN PHARMACEUTICA, N.V. |
发明人 |
ANZALONE, LUIGI;VILLANI, FRANK J.;TELEHA, CHRISTOPHER ALLAN;FEIBUSH, PENINA;FEGELY, BARRY |
| 分类号 |
C07D233/64;A61K31/4164;A61P1/00 |
主分类号 |
C07D233/64 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
