发明名称 |
TNF SUPERFAMILY COLLECTIN FUSION PROTEINS |
摘要 |
The present invention refers to a fusion protein comprising a TNF-superfamily (TNFSF) cytokine or a receptor binding domain thereof fused to a collectin trimerization domain, to a nucleic acid molecule encoding the fusion protein, and to a cell comprising the nucleic acid molecule. The fusion protein is present as a trimeric complex or as an oligomer thereof. The fusion protein, the nucleic acid, and the cell is suitable as pharmaceutical composition or for therapeutic, diagnostic and/or research applications. |
申请公布号 |
EP2176288(A2) |
申请公布日期 |
2010.04.21 |
申请号 |
EP20080773964 |
申请日期 |
2008.07.10 |
申请人 |
APOGENIX GMBH |
发明人 |
HILL, OLIVER;GIEFFERS, CHRISTIAN;THIEMANN, MEINOLF;BRANSCHÄDEL, MARCUS |
分类号 |
C07K14/525;A61K38/19;C12N5/10;C12N15/28;C12N15/62 |
主分类号 |
C07K14/525 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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