发明名称 POLYPEPTIDES, ANTIBODY VARIABLE DOMAINS AND ANTAGONISTS
摘要 The invention relates to anti-VEGF polypeptides and antibody single variable domains (dAbs) that are resistant to degradation by a protease, as well as antagonists comprising these. The polypeptides, dAbs and antagonists are useful for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient, as well as for treating cancer and inflammatory disease, such as arthritis.
申请公布号 KR20100040840(A) 申请公布日期 2010.04.21
申请号 KR20107000206 申请日期 2008.06.03
申请人 DOMANTIS LIMITED 发明人 STEWARD MICHAEL;PUPECKA MALGORZATA;TOMLINSON IAN;ENEVER CAROLYN;JESPERS LAURENT;BATUWANGALA THIL DINUK
分类号 C07K16/22;A61P35/00;C07K16/28;C12N15/63 主分类号 C07K16/22
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