发明名称 |
Compositions and methods for terminating a sequencing reaction at a specific location in a target DNA template |
摘要 |
Compositions and methods for sequencing a template polynucleotide comprising a sequence of interest are provided herein. The compositions and methods employ at least one blocking probe that is designed to bind in a sequence-specific manner to a blocking sequence such that primer extension beyond the site where the blocking probe binds is reduced or prevented.
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申请公布号 |
US7700287(B2) |
申请公布日期 |
2010.04.20 |
申请号 |
US20060341321 |
申请日期 |
2006.01.27 |
申请人 |
LIFE TECHNOLOGIES CORPORATION |
发明人 |
CHEN SHIAW-MIN;BRANDIS JOHN W. |
分类号 |
C12Q1/68;C07H21/04;C12P19/34 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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