发明名称 |
Recombinant proteins containing Shiga-like toxin and vascular endothelial growth factor fragments |
摘要 |
The present invention is directed to an isolated polypeptide including: (1) the A subunit of Shiga-like bacterial toxin, wherein said subunit has the nucleic acid sequence of SEQ ID NO:9; and (2) human vascular endothelial growth factor wherein the growth factor has the nucleic acid sequence of SEQ ID NO:10; wherein the isolated polypeptide possesses ribosome inactivating activity. The present invention is also directed to compositions for inhibiting endothelial cell growth in a patient.
|
申请公布号 |
US7700557(B2) |
申请公布日期 |
2010.04.20 |
申请号 |
US20070891863 |
申请日期 |
2007.08.14 |
申请人 |
SIBTECH, INC. |
发明人 |
BACKER MARINA V.;BACKER JOSEPH M. |
分类号 |
A61K38/18;C12N15/09;A61K38/00;A61P9/10;A61P9/14;A61P27/02;A61P29/00;A61P35/00;A61P35/02;A61P35/04;A61P43/00;C07K14/245;C07K14/25;C07K14/475;C07K14/52;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12Q1/02 |
主分类号 |
A61K38/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|