| 发明名称 |
Truncated baff receptors |
| 摘要 |
The disclosure provides a non-naturally occurring BAFF-R glycoprotein having a deletion in the extracellular domain which results in an altered 0-linked glycosylation pattern. The disclosure also provides methods and pharmaceutical compositions for treating B-cell- and T-cell-mediated disorders.
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| 申请公布号 |
US7700317(B2) |
申请公布日期 |
2010.04.20 |
| 申请号 |
US20040550961 |
申请日期 |
2004.03.26 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
AMBROSE CHRISTINE;THOMPSON JEFFREY;HSU YEN-MING;WEN DINGYI;SUN YAPING |
| 分类号 |
C12P21/00;A61K38/00;A61K38/17;A61K39/395;A61P37/00;C07H21/04;C07K14/705;C07K14/715;C07K16/00;C07K16/18;C07K19/00;C12N;C12N1/00;C12N1/20;C12N5/00;C12N15/00;C12N15/12;C12N15/13;C12N15/62 |
主分类号 |
C12P21/00 |
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