发明名称 BICYCLISCHE ANILIDSPIROLACTAME ALS ANTAGONISTEN DES CGRP-REZEPTORS
摘要 <p>The present invention is directed to compounds of Formula I: (where variables A1, A2, B, J, K, m, n, R4, R5a, R5b and R5c are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.</p>
申请公布号 AT464305(T) 申请公布日期 2010.04.15
申请号 AT20050795448T 申请日期 2005.09.09
申请人 MERCK SHARP & DOHME CORP. 发明人 BELL, IAN;THEBERGE, CORY;STUMP, CRAIG;ZHANG, XUFANG;GALLICCHIO, STEVEN;ZARTMAN, C.
分类号 C07D403/02;A61K31/44;A61K31/4965;A61K31/517;C07D221/02;C07D239/00;C07D241/00;C07D401/00 主分类号 C07D403/02
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