发明名称 |
PROCESS FOR THE PREPARATION OF DIHYDROXY ESTERS AND DERIVATIVES THEREOF |
摘要 |
A process is provided for the preparation of a compound of formula (5)
wherein R represents an optionally substituted hydrocarbyl group and X represents a hydrocarbyl linking group. The process comprises either the stereoselective reduction of the keto group in a dihydroxy keto precursor followed by selective esterification of a primary hydroxy, or selective esterification of a primary hydroxy of a dihydroxy keto precursor followed by stereoselective reduction of the keto group. |
申请公布号 |
PT1726658(E) |
申请公布日期 |
2010.04.15 |
申请号 |
PT20060019415T |
申请日期 |
2001.05.01 |
申请人 |
ASTRAZENECA UK LIMITED |
发明人 |
CHRISTOPHER DAVID REEVE;ANDREW JOHN BLACKER;ROBERT ANTHONY HOLT |
分类号 |
C12P7/62;C07C67/03;C07C69/675;C07D319/04;C07D319/06;C12N9/20;C12N15/54;C12P17/06;C12R1/84 |
主分类号 |
C12P7/62 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|