MICROORGANISM COMPRISING MODIFIED PURC GENE AND PROCESS FOR PRODUCTION METHOD OF INOSINE USING THE SAME

摘要

PURPOSE: A microorganism having modified purC gene is provided to enhance translation efficiency and translation initiation complex formation stability. CONSTITUTION: A Corynebacterium sp. microorganism having modified purC gene has modified initiation codon usage or Shine-Dalgarno sequence of Phosphoribosylaminoimidazolesuccinocarboxamide synthase. The microorganism is Corynebacterium ammoniagenes. The purC gene has a sequence of sequence number 9. The modified purC gene comprises a sequence of sequence number 1 or 2.