| 发明名称 |
NEW AMIDE COMPOUNDS AS BOOSTERS OF ANTIVIRALS |
| 摘要 |
The present invention relates to compounds that have CYP450 inhibiting properties and are therefore useful as boosters of certain drugs, i.e. they are able to increase at least one of the pharmacokinetic variables of certain drugs when co-administered. The invention further provides the use of said compounds as improvers of the bioavailability of certain drugs. Methods for the preparation of the compounds of the invention and pharmaceutical compositions comprising these compounds are also provided.
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| 申请公布号 |
CA2739673(A1) |
申请公布日期 |
2010.04.15 |
| 申请号 |
CA20092739673 |
申请日期 |
2009.10.07 |
| 申请人 |
TIBOTEC PHARMACEUTICALS |
发明人 |
JONCKERS, TIM HUGO MARIA;SCHEPENS, WIM BERT GRIET;HACHE, GEERWIN YVONNE PAUL;HALLENBERGER, BEATE SABINE;SASAKI, JENNIFER CHIYOMI;BAUMEISTER, JUDITH EVA;VAN 'T KLOOSTER, GERBEN ALBERT ELEUTHERIUS |
| 分类号 |
C07D277/24;A61K31/426;A61K31/427;A61P31/12;A61P31/18;C07D417/12 |
主分类号 |
C07D277/24 |
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