POLYMER-BIOACTIVE AGENT CONJUGATES

摘要

A bioerodible polymer - bioactive agent conjugate comprising as part of its polymer backbone a moiety of general formula (I) wherein: A and B, which may be the same or different, represent the remainder of the polymer backbone and are (i) attached to the -O-R(ZD)-O- moiety as shown in formula (I) via a bioerodible moiety, and (ii) each formed from monomeric units that are coupled via a bioerodible moiety; R represents a linear or branched optionally substituted hydrocarbon; Z is a linking group; and D is a releasable bioactive agent.