DETECTING AND HANDLING COINCIDENCE IN PARTICLE ANALYSIS
摘要
Methods and systems substantially eliminate data representative of coincident events from particle analyzer data. A fluid sample containing particles for analysis is prepared. Using an electrical or optical measurement device, signals are sensed. Each signal corresponds to events detected in a sub-sample of the fluid sample flowing through a measurement region in the particle analyzer. The existence of coincidence in the events is determined based on measuring a peak and first and second points of each of the signals. The first and second points have a signal value corresponding to a predetermined portion of the peak. Results data based upon the coincident events and non-coincident events is generated. The results data is then analyzed. In various examples, the method is applicable to a variety of particle types, and may be implemented on different types of particle analyzers including hematology analyzer and flow cytometers.
申请公布号
WO2010042401(A1)
申请公布日期
2010.04.15
申请号
WO2009US59363
申请日期
2009.10.02
申请人
BECKMAN COULTER, INC.;BRITTON, TED, W.;LU, JIULIU;ROSE, JEFFREY, L.