发明名称 |
Enzymes resistant to photodamage |
摘要 |
Provided are compositions comprising modified DNA polymerases that exhibit improved photostability compared to the parental polymerases from which they were derived. Provided are methods for generating enzymes, such as DNA polymerases, with the aforementioned phenotype. Provided are methods of using polymerases with increased resistance to photodamage to make a DNA or to sequence a DNA template.
|
申请公布号 |
US2010093555(A1) |
申请公布日期 |
2010.04.15 |
申请号 |
US20090384110 |
申请日期 |
2009.03.30 |
申请人 |
PACIFIC BIOSCIENCES OF CALIFORNIA, INC. |
发明人 |
BJORNSON KEITH;CLARK SONYA;PARK INSIL;CHRISTIANS FRED |
分类号 |
C40B30/04;C07H21/04;C12N9/10;C12N9/96;C12P19/34;C12Q1/48;C12Q1/68 |
主分类号 |
C40B30/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|