The present invention relates to bacteriophage adhesion proteins binding to the O-antigen of gram negative bacteria, lacking the ability of binding to a bacteriophage and of hydrolysing lipopolysaccharides. The invention further relates to nucleic acid molecules comprising a sequence encoding the proteins according to the present invention. In addition, the present invention relates to a method for generating bacteriophage adhesion proteins according to the present invention. The invention further relates to the use of said proteins and methods of detection, purification and enrichment of bacteria.
申请公布号
WO2010000854(A3)
申请公布日期
2010.04.15
申请号
WO2009EP58453
申请日期
2009.07.03
申请人
BIOMERIEUX S.A.;BIEBL, MANFRED;GRASSL, RENATE;WALTER, MONIKA;MILLER, STEFAN
发明人
BIEBL, MANFRED;GRASSL, RENATE;WALTER, MONIKA;MILLER, STEFAN