A METHOD OF DELIVERING FUNCTIONAL AGENTS ACROSS THE BLOOD-BRAIN BARRIER

摘要

The present invention provides a method of delivering a functional agent across the blood brain barrier so that the functional agent is delivered into the brain of the subject, the method comprising the step of administering a polymeric capsule associated with said functional agent to the subject whereby the polymeric capsule crosses the blood brain barrier and wherein the polymeric capsule is from 300 nm to 2000 nm in diameter and comprises a polymeric shell defining an internal cavity. Further provided is a method of delivering a polymeric capsule across the blood brain barrier. The present invention also provides a polymeric capsule, or a polymeric capsule associated with a functional agent, which is suitable for use in a method of the present invention.