发明名称 HIV PROTEASE INHIBITORS
摘要 Compounds of Formula I are disclosed: (I), wherein XA, k, R1, R2, R3, R4, R5, R5A, R6, R6A, R7 and R8 are defined herein. The compounds encompassed by Formula I include compounds which are HIV protease inhibitors and other compounds which can be metabolized in vivo to HIV protease inhibitors. The compounds and their pharmaceutically acceptable salts are useful for the prophylaxis or treatment of infection by HIV and the prophylaxis, treatment, or delay in the onset of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
申请公布号 US2010093811(A1) 申请公布日期 2010.04.15
申请号 US20080523200 申请日期 2008.09.22
申请人 COBURN CRAIG A;VACCA JOSEPH P;RAJAPAKSE HEMAKA A;JONES KRISTEN L G;NANTERMET PHILIPPE;BARROW JAMES C;MOORE KEITH P;SHARIK STEVEN S;THEBERGE CORY;WALJI ABBAS M 发明人 COBURN CRAIG A.;VACCA JOSEPH P.;RAJAPAKSE HEMAKA A.;JONES KRISTEN L.G.;NANTERMET PHILIPPE;BARROW JAMES C.;MOORE KEITH P.;SHARIK STEVEN S.;THEBERGE CORY;WALJI ABBAS M.
分类号 A61K31/44;A61K31/18;A61K31/27;A61K31/426;A61P31/18;C07C271/06;C07C311/15;C07D213/55;C07D277/62 主分类号 A61K31/44
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