发明名称 |
ANTI-ALLERGIC AGENT COMPRISING RXR AGONIST AS ACTIVE INGREDIENT |
摘要 |
<p>Disclosed is a novel anti-allergic agent which can act on allergic diseases effectively and has reduced adverse side effects. The anti-allergic agent comprises an RXR agonist as an active ingredient. The RXR agonist to be used as the active ingredient for the anti-allergic agent can prevent allergic diseases through a different mechanism of action from that of the glucocorticoid receptor activation activity of a steroid. While a steroid produces various adverse side effects through a glucocorticoid receptor (GR) which is one of nuclear receptors, the RXR agonist does not act on a GR and therefore can be used as a novel anti-allergic agent that can act on allergic diseases effectively and has reduced adverse side effects.</p> |
申请公布号 |
WO2010041449(A1) |
申请公布日期 |
2010.04.15 |
申请号 |
WO2009JP05235 |
申请日期 |
2009.10.08 |
申请人 |
SUGIMOTO, YUKIO;NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY;KAKUTA, HIROKI |
发明人 |
SUGIMOTO, YUKIO;KAKUTA, HIROKI |
分类号 |
C07D213/80;A61K45/00;A61K31/455;A61P37/08;A61P43/00 |
主分类号 |
C07D213/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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